Wogonoside Effects on Hyperosmotic Stress in Human Corneal Epithelial Cells

Yuan Zhong published this dataset on figshare in 2026. It contains data from a study investigating the protective effects of the flavonoid Wogonoside against hyperosmotic stress in human corneal epithelial cells. The dataset likely includes results from network pharmacology, molecular docking, and in vitro cell assays measuring viability, apoptosis, and inflammatory markers.

Use Cases

• Modeling drug-target interactions based on network pharmacology and molecular docking results.
• Analyzing cell viability and apoptosis rates under hyperosmotic stress conditions.
• Investigating inflammatory mediator levels such as IL-1β, IL-6, and MMP-9.
• Studying PI3K/AKT signaling pathway activation and inhibition in corneal epithelial cells.

Strengths

• Dataset is licensed under CC-BY-4.0, permitting open sharing and reuse.
• The study description details specific experimental conditions, including a 500 mOsm hyperosmotic medium and defined inhibitor concentrations.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small at 8.5 MB, suggesting limited scale.

Provenance

Source

figshare

Collection Method

Data was generated from in vitro experiments on human corneal epithelial cells, combined with computational network pharmacology and molecular docking analyses.

Time Range

The study was published in 2026, but the specific experimental timeframe is not provided.

Freshness

Last updated 2026-05-04 04:24:23; freshness should be verified.

Geography

The geographic origin of the data or the study institution is not specified.