YKT6 Gene Expression and Prognostic Data for Breast Cancer

Meilin Zhang published a dataset on figshare in April 2026 investigating the YKT6 gene's role in breast cancer. The data, derived from public datasets, clinic samples, and tissue microarrays, links YKT6 overexpression to poor prognosis, advanced tumor stages, and immune cell infiltration. It is a 1.1 MB PDF file available under a CC-BY-4.0 license.

Use Cases

• Identify prognostic biomarkers for breast cancer based on YKT6 expression levels.
• Analyze correlations between gene expression and tumor-infiltrating immune cells.
• Investigate the relationship between gene expression and tumor mutation burden (TMB).
• Study the functional role of YKT6 in cancer cell proliferation, invasion, and migration.
• Explore biological pathways like cell cycle, autophagy, apoptosis, and ferroptosis influenced by YKT6.

Strengths

• Data integrates multiple sources including public datasets, clinic samples, and tissue microarrays.
• Analysis links YKT6 expression to specific clinical outcomes like advanced tumor stages and distant metastasis.
• Includes functional validation from cellular assays such as proliferation, invasion, migration, and apoptosis tests.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The primary data file is a 1.1 MB PDF, which may require extraction to access structured data.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Meilin Zhang

Collection Method

Combined analysis of public datasets (e.g., TCGA), clinic samples, tissue microarrays (TMA), and cellular functional assays.

Freshness

Last updated 2026-04-22 05:47:27; freshness should be verified.