ZFP36L1 and Autophagy in Murine Norovirus Replication: Experimental Data

Murine norovirus 1 (MNV-1) infection data investigating the antiviral role of RNA-binding protein ZFP36L1. The 90.4 KB PDF, authored by Malabika Bhowmik and last updated April 2026, details how ZFP36L1 overexpression suppressed viral replication and reduced autophagy markers like ATG13 and LC3-I to LC3-II conversion. Results suggest ZFP36L1-mediated autophagy suppression contributes to reduced MNV-1 titer.

Use Cases

• Study the antiviral effects of ZFP36L1 protein based on overexpression and knockdown experiments described
• Analyze the relationship between norovirus replication and autophagy based on measured markers like ATG13 and LC3 conversion
• Investigate pharmacological modulation of autophagy using rapamycin or 3-methyladenine in the context of viral infection

Strengths

• Data is associated with a specific, peer-reviewed research finding on ZFP36L1's role in norovirus infection
• The 90.4 KB PDF is openly licensed under CC-BY-4.0 for reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small (90.4 KB), indicating limited scope

Provenance

Source

figshare

Collection Method

Likely contains experimental results from virology and molecular biology assays, as described in the associated research.

Freshness

Last updated 2026-04-21 09:23:41; freshness should be verified