Standardized Rat Model of Maxillary Anterior Periodontal Soft Tissue Defect

A 7.5 MB PDF document authored by Ruoxuan Huang and last updated in April 2026. The file describes the establishment of a standardized, reproducible rat model for creating a 4x2 mm soft tissue defect in the maxillary anterior labial region. The model is intended for the in vivo evaluation of graft materials and healing processes in periodontal soft tissue reconstruction.

Use Cases

• Benchmarking graft material performance based on the described standardized defect model.
• Studying healing patterns and tissue integration based on the sequential clinical and histological analyses mentioned.
• Evaluating angiogenesis and immune response during soft tissue regeneration as described in the results.
• Screening graft materials prior to large-animal studies based on the model's translational relevance discussed.

Strengths

• Documentation includes specific defect dimensions (4 x 2 mm) and details on evaluation methods like H&E and Masson's trichrome staining.
• The model is described as having low complication rates and high reproducibility.
• Licensed under CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• The dataset is a 7.5 MB PDF; the underlying raw experimental data (e.g., measurements, images) are not directly provided.
• Row count and column-level documentation are absent; data semantics must be extracted from the document text.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Research study and documentation.

Time Range

Publication date not specified; document last updated April 2026.

Freshness

Last updated 2026-04-20 05:23:13; freshness should be verified.

Geography

Laboratory research, location unspecified.