Amomum Tsaoko Extract Data: Bioactivity in Colitis and Necroptosis Models

29.2 KB of experimental data from a study investigating Amomum tsaoko (Cao Guo) extract for ulcerative colitis treatment. The dataset likely contains results from bioinformatics analysis, in vitro necroptosis models, and mouse model validation, exploring targets like STAT3, RIPK1, RIPK3, and MLKL. Author Yuanyuan Wang published this work under a CC-BY-4.0 license on figshare in March 2026.

Use Cases

• Analyzing correlations between ulcerative colitis and necroptosis pathways based on GEO data analysis mentioned in the description
• Modeling the inhibitory effects of plant extracts on RIPK1, RIPK3, and MLKL phosphorylation based on in vitro assay results
• Investigating the role of the STAT3 signaling pathway in colitis treatment based on bioinformatics and experimental validation
• Evaluating changes in disease activity index (DAI) and tight junction protein expression (ZO-1, Occludin) in animal models

Strengths

• Dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution
• Description provides a detailed scientific context for the likely experimental results
• File is small (29.2 KB), facilitating quick download and inspection

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download
• The dataset is very small (29.2 KB), indicating limited scope and likely summary-level results rather than raw high-throughput data

Provenance

Source

Author Yuanyuan Wang, published on figshare

Collection Method

Likely contains summarized results from bioinformatics analysis, chemical composition analysis, in vitro assays, and mouse model experiments.

Time Range

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Freshness

Last updated 2026-03-18 07:43:15; freshness should be verified

Geography

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