Meta-Analysis of PCOS and Metabolic Syndrome in Adolescents

A systematic review and meta-analysis by Yuhui Tu, published in 2026, synthesizes evidence from 13 observational studies. The analysis includes data from 1,789 adolescent participants (1,005 with PCOS) to quantify associations with metabolic syndrome and its components.

Use Cases

• Calculate pooled odds ratios for metabolic syndrome risk in adolescents with PCOS using the provided OR and 95% CI data.
• Analyze weighted mean differences for specific metabolic components like waist circumference, systolic blood pressure, and triglyceride levels.
• Compare the strength of associations across different study designs (5 cross-sectional, 6 case-control, 2 cohort) included in the meta-analysis.

Strengths

• Aggregates evidence from 13 distinct observational studies for a more reliable conclusion.
• Includes data from 1,789 total participants, with 1,005 specifically diagnosed with PCOS.
• Reports specific quantitative measures including odds ratios and weighted mean differences with 95% confidence intervals.

Limitations

• The underlying raw participant-level data is not provided; only the synthesized meta-analysis results are available.
• The 13 included studies may have heterogeneous methodologies and populations, potentially affecting pooled estimates.
• The dataset is a 17.5 MB document file, not a structured table, limiting direct computational analysis.

Provenance

Source

Yuhui Tu via figshare.

Collection Method

Systematic review and meta-analysis of studies from PubMed, Embase, Cochrane Library, and Web of Science.

Time Range

Studies published up to September 2025.

Freshness

Last updated March 2026.

Geography

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