Environmental E. coli Strains with Colistin Resistance and Oxidant Tolerance

A 2026 dataset by Asmaa Al-Mesaifri characterizes Escherichia coli strains isolated from mixed wastewater. The data includes measurements of resistance to last-resort antibiotic colistin (IC50 values 6.5–27.3 μg/mL) and other antibiotics, as well as tolerance to hydrogen peroxide and UV radiation. Whole genome sequencing data reveals missense mutations in DNA repair genes associated with oxidant resistance.

Use Cases

• Modeling antibiotic resistance levels based on IC50 values for colistin and other drugs mentioned in the description
• Investigating genetic mutations linked to oxidant tolerance based on whole genome sequencing data
• Analyzing co-resistance patterns to multiple antibiotic classes described in the study

Strengths

• Includes specific quantitative resistance measurements (IC50 values ranging from 6.5 to 27.3 μg/mL)
• Links phenotypic resistance to genomic data via whole genome sequencing analysis
• Released under a permissive CC-BY-4.0 license for reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset is very small (10.9 KB), indicating limited scope

Provenance

Source

Asmaa Al-Mesaifri via figshare

Collection Method

E. coli strains were isolated from mixed wastewater and characterized biochemically and genomically.

Freshness

Last updated 2026-06-02 22:02:21