Biogenic Silver Nanoparticle Data for Osteomyelitis Treatment Research

Munirah F. Aldayel's research presents a novel green-synthesized silver nanoparticle formulation with dual antibacterial and bone-forming properties. The dataset, shared on figshare in May 2026, includes experimental results from a Staphylococcus aureus-induced osteomyelitis mouse model. It details the formulation's significant reduction of bacterial burden and its promotion of osteocalcin-positive osteoblasts and collagen deposition in bone.

Use Cases

• Training models to predict antibacterial efficacy based on nanoparticle synthesis parameters.
• Analyzing the relationship between nanoparticle treatment and osteoblast activity markers like osteocalcin.
• Studying the synergistic effects of plant extract phytochemicals on nanoparticle performance for bone regeneration.
• Benchmarking new antibacterial nanomaterials against the reported MIC and MBC values against Staphylococcus aureus.

Strengths

• Dataset is associated with a specific, peer-reviewed research methodology using a mouse model of osteomyelitis.
• Results include concrete biological endpoints such as reduced CD68-positive macrophage infiltration and increased osteoid thickness.
• The data is openly shared under a CC-BY-4.0 license, permitting reuse and adaptation.

Limitations

• The dataset is a single 835.7 KB PDF file; the underlying structured data (e.g., raw measurements, column definitions) is not provided.
• Row count and data granularity are unknown, limiting suitability for large-scale statistical analysis.
• Column-level documentation is absent; field semantics must be inferred from the research paper.

Provenance

Source

figshare

Collection Method

Experimental research involving green synthesis of silver nanoparticles and in vivo mouse model testing.

Freshness

Last updated 2026-05-26 04:37:03; freshness should be verified.