Data Sheet 2_Clindamycin susceptibility and virulence characterization of Listeria monocyt

62 Listeria monocytogenes strains isolated from meat and meat-processing environments were analyzed for clindamycin susceptibility and virulence. The dataset, authored by Aida Pérez-Baltar and last updated in May 2026, includes phenotypic MIC values, detection of resistance genes like vgaG and fosX, and genomic analysis of virulence factors such as prfA and inlA. Findings show 22.6% of strains were phenotypically susceptible to clindamycin, with correlations observed between susceptibility and truncated virulence genes.

Use Cases

• Training models to predict antimicrobial susceptibility phenotypes based on genomic markers like vgaG mutations.
• Analyzing co-occurrence patterns between intrinsic resistance genes (fosX, norB, mprF, sul) and virulence factor impairments.
• Studying the population genetics of Listeria monocytogenes by correlating clonal complexes (CC31, CC155) with hypovirulent phenotypes.

Strengths

• Includes 62 bacterial strains with both phenotypic (disk diffusion, MIC) and genotypic (WGS) characterization.
• Reports specific MIC values (0.25–0.5 μg/mL) for susceptible strains and identifies a deleterious mutation in the vgaG gene.
• Links clindamycin susceptibility to concrete genomic alterations in virulence genes (prfA, inlA, inlB, actA, plcA).

Limitations

• Row count for the underlying data table is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (179.0 KB), indicating limited scope.

Provenance

Source

Aida Pérez-Baltar via figshare.

Collection Method

Strains were isolated from meat and meat-processing environments, with susceptibility tested via disk diffusion and MIC, and genomes analyzed via whole-genome sequencing.

Freshness

Last updated 2026-05-21 05:44:23; freshness should be verified.