Data Sheet 2_Clinical significance and simultaneous microevolution of two closely-related nontuberculous mycobacteria species.xlsx

Figshare hosts a dataset from a single-case study investigating pulmonary co-infection by Mycobacterium septicum and Mycolicibacterium nivoides. The data includes clinical findings, microbiological assay results, genomic sequencing for 20 colonies per species, and virulence assessments using Galleria mellonella. Author Chengcheng Wang published this 18.9 KB Excel file in April 2026.

Use Cases

• Analyze genomic heterogeneity by comparing sequences from 20 M. septicum and 20 M. nivoides colonies.
• Correlate specific gene mutations (α/β hydrolase, papA2) with virulence scores from the Galleria mellonella model.
• Review clinical case data to classify M. septicum roles as pathogen, colonizer, or contaminant.
• Validate genome classification methods using re-analyzed data from 16 publicly-accessible genomes.

Strengths

• Includes genomic sequencing data for 20 bacterial colonies from each of the two mycobacterial species.
• Integrates multiple data types: clinical records, microbiological assays, genomic sequences, and model virulence scores.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Limited scope with data derived from a single clinical case study.
• Small file size of 18.9 KB indicates a focused, not large-scale, dataset.
• Geographic and demographic coverage of the single case is unknown.

Provenance

Source

Chengcheng Wang via figshare.

Collection Method

Data gathered from a detailed single-case study involving clinical review, lab assays, genome sequencing, and literature analysis.

Time Range

Temporal coverage of the primary case study is not specified.

Freshness

Last updated in April 2026.

Geography

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