CLL Cell-Derived Soluble Factors and Normal B Cell Functionality Assay Data

Michelle Maria Elbert published a dataset on figshare in 2026 investigating the influence of chronic lymphocytic leukemia (CLL) cell-derived soluble factors on normal B cell functionality. The data likely contains results from in vitro functional B-cell assays measuring plasma cell differentiation, proliferation, cell death, and activation markers (CD80, CD86, CD25). The 3.9 MB dataset is available under a CC-BY-4.0 license.

Use Cases

• Analyze the effect of CLL patient serum on B-cell proliferation based on the described assay.
• Compare B-cell activation levels using CD80, CD86, and CD25 markers between CLL and control conditions.
• Investigate plasma cell differentiation outcomes from T-cell-dependent stimulation of B cells.
• Assess cell death levels in normal B cells cultured with CLL-conditioned medium.

Strengths

• Data is published under a permissive CC-BY-4.0 license.
• The experimental design includes control conditions from healthy individuals.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

In vitro functional B-cell assays using serum from CLL patients and conditioned medium from CLL cells cultivated with stromal cells.

Freshness

Last updated 2026-05-15 05:52:08; freshness should be verified.