LZH and ZJ Combined Treatment: Molecular Mechanisms in Skin Wound Healing
by Li Liu·Updated 3d ago
30.3 KB1files
Available on 1 platform
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Description
Li Liu authored a research document on figshare, last updated June 2, 2026, describing a study on traditional Chinese medicinal formulations. The document details the effects of Lingzhi Huang capsules and Zeng Jian Health Tonic, individually and combined, on accelerating skin wound healing in a mouse model. It includes results from LC-MS/MS chemical analysis, histopathology, immunofluorescence, Western blotting, protein arrays, and in vitro experiments with human umbilical vein endothelial cells.
Use Cases
Study the anti-ferroptotic effects of traditional Chinese medicine based on GPX4, SLC7A11, and FTH1 expression data mentioned in the description.
Analyze angiogenesis promotion in wound healing based on CD31 and VEGF expression results described.
Investigate the role of BMP5 as a regulatory target in combined treatment effects as identified through network pharmacology.
Examine oxidative stress markers in wound healing based on described measurements of ROS, SOD, GSH, and MDA levels.
Strengths
Document is shared under a permissive CC-BY-4.0 license.
Research methodology is described in detail, including in vivo mouse models and in vitro HUVEC experiments.
The study identifies a specific molecular mechanism involving BMP5-mediated inhibition of ferroptosis.
Limitations
The dataset is a 30.3 KB DOCX file, indicating it is a text document, not a structured data table.
Row count and column-level documentation are absent; data semantics must be inferred from the narrative.
Description metadata is limited; actual data quality requires manual inspection after download.
Provenance
Source
figshare, author Li Liu.
Collection Method
Research involving LC-MS/MS chemical characterization, a mouse full-thickness skin wound model, histopathological analysis, immunofluorescence, Western blotting, protein antibody arrays, and in vitro cell culture experiments.
Freshness
Last updated 2026-06-02 05:42:34; freshness should be verified.
The primary file is a DOCX document, not a structured data file (e.g., CSV). Users should expect a research paper format.