Oncopig High-Grade Glioma Model: Tumor Growth and Surgical Resection Data

A research document describes a preclinical surgery model for high-grade glioma using ten Oncopigs. The study monitored tumor induction via viral vectors, tracked growth with MRI, and performed surgical resections, with results from six animals showing tumor onset and volume ranges. The dataset was authored by Caleb Y. Kwon and last updated on April 20, 2026.

Use Cases

• Evaluating tumor growth kinetics based on MRI monitoring data described in the study
• Assessing the pathological fidelity of animal models for human high-grade glioma based on histopathological analysis
• Testing fluorescence-guided surgical techniques based on the ALA-PpIX fluorescence results mentioned

Strengths

• Includes specific quantitative results: median tumor onset time of 24 days and a range of 13 to 104 days
• Reports concrete tumor volume measurements ranging from 250 to 2000 mm3
• Provides pathological validation, with tumors in six subjects showing features consistent with human high-grade glioma

Limitations

• Dataset is a 14.3 KB DOCX file, indicating a very limited scope likely focused on textual results rather than raw experimental data
• Row count and column-level documentation are absent; data structure and variables must be inferred from the document
• The sample size is small, with tumors observed in only six out of ten subjects

Provenance

Source

figshare

Collection Method

Experimental study involving viral induction of tumors in a transgenic Oncopig model, followed by MRI monitoring and surgical procedures.

Freshness

Last updated 2026-04-20 09:56:23