Neuromodulation Trial Data on Tobacco Craving and Response Times

A secondary analysis of a randomized trial involving 23 tobacco-dependent adults who underwent a single rTMS session targeting either the left frontopolar cortex or vertex. The dataset includes response times and self-reported craving ratings from an image-based cue-reactivity paradigm conducted before and after stimulation. It examines the modulation of these implicit and explicit measures by stimulation site and their association with smoking outcomes.

Use Cases

• Analyze the Group × Time × Stimulus interaction effect on mean response time to smoking cues.
• Model response time as a function of self-reported craving to explore implicit motivational processes.
• Examine exploratory clinical associations between response time indices and smoking-related outcomes like tonic craving.
• Compare response time patterns between lFPC and vertex stimulation groups for smoking and neutral cues.

Strengths

• Data originates from a controlled randomized trial with 23 participants, providing a structured experimental context.
• Includes both behavioral (response time) and self-report (craving rating) measures for a multi-faceted analysis.
• Analysis is grounded in specific statistical results, such as a significant Group × Time × Stimulus effect (χ²(1) = 8.64, p = 0.003).

Limitations

• Small sample size of 23 participants limits statistical power and generalizability of findings.
• Exploratory clinical analyses did not reveal reliable associations with smoking outcomes, indicating preliminary nature.
• The dataset is contained within a 1.1 MB DOCX file, which may require extraction and structuring for computational analysis.

Provenance

Source

Larissa Vieira via figshare.

Collection Method

Secondary analysis of a randomized trial using an image-based cue-reactivity paradigm and rTMS intervention.

Time Range

Data collection timeframe not specified in input.

Freshness

Last updated on 2026-03-23.

Geography

Geographic coverage not specified in input.