Icaritin Effects on Allograft Rejection and Tumor Growth in Mice

A 625.2 KB research document from figshare details the dual role of icaritin in mouse models. Author Jinliang Duan published the work under a CC-BY-4.0 license, with a last update in March 2026. The study uses single-cell RNA sequencing and flow cytometry to analyze immune cell responses.

Use Cases

• Analyzing the effect of icaritin on Th1 cell differentiation based on scRNA-seq and flow cytometry data.
• Modeling the binding interaction between icaritin and the transcription factor CEBPB based on molecular docking simulations.
• Evaluating graft survival and tumor burden in a dual heart transplantation and tumor-bearing mouse model.

Strengths

• Document is under a permissive CC-BY-4.0 license.
• Last updated date is explicitly provided: 2026-03-18.

Limitations

• The dataset is a 625.2 KB DOCX file, indicating a limited scope of raw data.
• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The description is a research paper abstract; the underlying experimental data files are not detailed.

Provenance

Source

Jinliang Duan via figshare.

Collection Method

Experimental data from mouse models, single-cell RNA sequencing, and flow cytometry.

Time Range

The study period is not specified.

Freshness

Last updated 2026-03-18 05:34:53; freshness should be verified.

Geography

The geographic origin of the data is not specified.