Network Meta-Analysis of Non-Pharmacological Diabetic Foot Ulcer Interventions

24 randomized controlled trials evaluating 15 non-pharmacological interventions for diabetic foot ulcer healing. The meta-analysis, conducted by Jiaxing Zheng, compares outcomes like 12-week healing rate and healing time across treatments such as Negative Pressure Wound Therapy.

Use Cases

• Compare the relative effectiveness of 15 intervention types on the 12-week healing rate outcome.
• Rank interventions like Negative Pressure Wound Therapy + Standard Care using SUCRA scores for exploratory analysis.
• Analyze the reported healing time outcome across different combinations like Gas Therapy + Dressing Therapy + Standard Care.
• Assess the risk of bias across the 24 included trials using the Cochrane RoB 2.0 tool evaluation.

Strengths

• Systematic review protocol registered with PROSPERO (CRD420251122143).
• Analysis includes 24 randomized controlled trials sourced from 8 databases.
• Compares 15 distinct non-pharmacological intervention types for a specific condition.

Limitations

• Evidence certainty is limited by a small number of included studies and wide confidence intervals.
• Dataset is a 187.2 KB DOCX document containing analysis text, not structured tabular data.
• Conclusions rely on moderate-quality literature and require confirmation from larger RCTs.

Provenance

Source

figshare, authored by Jiaxing Zheng.

Collection Method

Systematic review and network meta-analysis of published randomized controlled trials.

Time Range

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Freshness

Last updated March 2026.

Geography

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