Data Sheet 2_Efficacy and safety of Buyang Huanwu Decoction combined with α-lipoic acid fo

A 2025 systematic review and meta-analysis of 12 randomized controlled trials involving 926 patients, evaluating the combination therapy for diabetic peripheral neuropathy. The dataset, created by Qi Yong, includes results on overall response rates, nerve conduction velocities, and oxidative stress markers. The analysis employed a multi-tiered framework to deconstruct heterogeneity in the evidence.

Use Cases

• Assessing treatment efficacy based on overall response rate and TCM syndrome score results from the meta-analysis.
• Analyzing heterogeneity in nerve conduction velocity outcomes using the described five-tiered analytical framework.
• Evaluating safety profiles based on adverse event data mentioned in the review.
• Examining trends in oxidative stress markers like SOD, MDA, and T-AOC reported in the included trials.

Strengths

• Includes data from 12 randomized controlled trials with a total of 926 patients.
• Provides specific effect size metrics, such as RR=1.24 for overall response rate and SMD=-0.76 for TCM syndrome scores.
• Applies a detailed methodological framework for heterogeneity deconstruction, including subgroup analysis and meta-regression.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small at 60.3 KB, indicating limited scope, likely containing summary results rather than raw patient-level data.

Provenance

Source

Systematic review conducted by the author, with trials sourced from databases including PubMed, Web of Science, and CNKI.

Collection Method

Meta-analysis of randomized controlled trials identified through a systematic literature search up to December 2025.

Time Range

Literature search covered studies up to December 2025.

Freshness

Last updated 2026-04-30 04:18:16; freshness should be verified.