Electroacupuncture Effects on Myocardial Ischemia via Exosomal miR-22-3p

Experimental data from a study investigating the cardioprotective mechanism of electroacupuncture in a rat model of myocardial ischemia-reperfusion injury. The dataset likely contains measurements of cardiac function, infarct area, serum enzyme levels, inflammatory factors, and gene/protein expression related to NLRP3 inflammasome-mediated pyroptosis. It was authored by Jian Xiong and last updated on June 1, 2026.

Use Cases

• Validate the role of exosomal miR-22-3p in cardioprotection based on small RNA sequencing results mentioned in the description
• Analyze the relationship between NLRP3 inflammasome activity and myocardial injury based on Western blot and RT-qPCR data
• Correlate electroacupuncture intervention with cardiac function and infarct size outcomes based on echocardiography and staining data
• Investigate serum exosome cargo changes post-treatment based on exosome isolation from patient and rat serum samples

Strengths

• Data is associated with a detailed, peer-reviewed research methodology described in the PDF
• Includes multi-modal validation from in vivo animal models and in vitro cell experiments
• License is CC-BY-4.0, permitting broad reuse with attribution

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect bias inherent to the specific animal model and experimental protocol used

Provenance

Source

figshare

Collection Method

Data generated from an experimental study using a rat model of myocardial ischemia-reperfusion injury and a cardiomyocyte hypoxia/reoxygenation model.

Freshness

Last updated 2026-06-01 09:12:48; freshness should be verified