Oral Mucosal Fungal Abundance and T Cell Metrics in Aging and HIV

A 402.7 KB PDF data sheet from figshare details associations between oral fungal colonization and immune cell populations. Author S. Jayaraman published the data under a CC-BY-4.0 license in March 2026. The dataset likely contains measurements of Candida abundance, T cell levels, and cytokine concentrations from analyses of gingival tissue and saliva.

Use Cases

• Correlating Candida species abundance with CD4+FOXP3+ regulatory T cell levels based on mucosal tissue analysis.
• Comparing fungal community composition (e.g., Saccharomycetales, Cryptococcus) between older and younger individuals.
• Analyzing relationships between salivary IL-6, soluble TLR-2, and T cell dysfunction metrics.
• Stratifying fungal colonization and immune marker data by HIV status and age group.

Strengths

• Data is derived from stratified analysis by both age (>60) and HIV status.
• Includes in vitro mechanistic insights linking Candida to Treg dysfunction via IL-6.
• Published under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring inference from the description.
• The dataset is small at 402.7 KB, indicating limited scope.
• Geographic and demographic details of the sample population are not provided.

Provenance

Source

figshare, author S. Jayaraman.

Collection Method

Likely contains aggregated results from mucosal sample analysis, in vitro experiments, and statistical correlations.

Freshness

Last updated 2026-03-19 05:17:37.