Enterococcus faecium HDRsEf1 Effects on Gut Microbiota and Metabolites in Mice and Pigs

Shuaifei Feng's research data, published on figshare in April 2026, investigates the probiotic effects of Enterococcus faecium HDRsEf1. The dataset likely contains measurements from mouse and pig models, including inflammatory markers, oxidative stress indicators, gut microbiota composition, and fecal metabolite profiles. The study aims to show how this probiotic modulates the gut environment to enhance host health.

Use Cases

• Analyze correlations between probiotic administration and inflammatory cytokine levels (IL-1β, IL-6, TNF α, IL-10) based on the described experimental results.
• Model changes in gut microbiota composition, such as the promotion of Ruminococcus and suppression of Acinetobacter, based on the description.
• Investigate links between probiotic intervention and antioxidant enzyme activity (SOD) and oxidative stress markers (MDA) as mentioned in the study.
• Explore associations between microbial shifts and anti-inflammatory metabolite enrichment in fecal samples described in the metabolomic analysis.

Strengths

• Data is derived from controlled animal experiments in two models (mice and pigs), suggesting a structured experimental design.
• Specific biological markers are measured, including cytokines (IL-1β, IL-6, TNF-α, IL-10), oxidative stress indicators (MDA, SOD), and microbiota genera.
• The dataset is openly shared under a CC-BY-4.0 license, permitting reuse with attribution.

Limitations

• The dataset is very small (391.1 KB), indicating limited scope and likely a summary of results rather than raw experimental data.
• Column-level documentation is absent; field semantics and data structure must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

Shuaifei Feng via figshare.

Collection Method

Experimental data from DSS-induced colitis in mice and nursery pig models.

Time Range

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Freshness

Last updated 2026-04-15 04:37:10; freshness should be verified.

Geography

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