Data Sheet 2_Exploring In situ neuroprotective mechanisms of nicotine in an MPTP-Induced P

A 28.1 KB Excel file contains spatial metabolomics data from a Parkinson's disease study. Lutao Xu authored this dataset, which was last updated on May 1, 2026. It maps metabolic changes across brain regions in an MPTP-induced rat model and examines the neuroprotective effects of nicotine.

Use Cases

• Analyze region-dependent metabolic disruption in Parkinson's disease based on spatial metabolomics data.
• Investigate nicotine's effect on neurotransmitter balance based on dopamine, GABA, and serotonin metabolite levels.
• Study recovery of membrane lipid homeostasis based on glycerophospholipid metabolism pathway analysis.
• Examine mitochondrial stress markers based on AMP accumulation and glutathione level changes.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• The description provides a detailed scientific context for the metabolomics findings.
• File size is 28.1 KB, making it quick to download and inspect.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (28.1 KB), indicating limited scope or a summary dataset.

Provenance

Source

figshare

Collection Method

Data likely generated using airflow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI) on rat brain tissue.

Freshness

Last updated 2026-05-01 05:24:51; freshness should be verified.