Fecal Microbiota Transplantation Effects in HIV-Infected Mice on ART

Saroj Chandra Lohani's dataset compares gut microbiota and gene expression in HIV-infected double humanized-BLT mice treated with antiretroviral therapy alone versus with fecal microbiota transplantation. The 80.5 KB Excel file contains results from a multi-omics approach including 16S rRNA sequencing and RNA-seq. It was last updated on June 3, 2026.

Use Cases

• Compare gut microbial composition changes based on 16S rRNA sequencing data mentioned in the description
• Analyze transcriptomic changes in intestinal tissue based on RNA-seq data mentioned in the description
• Correlate plasma inflammatory marker levels (e.g., CD62E, sCD14) with treatment groups described
• Investigate pathways like extracellular matrix organization predicted from the gene expression data

Strengths

• Data is derived from a multi-omics approach combining 16S rRNA sequencing and RNA-seq
• Includes quantification of specific plasma inflammatory markers: CD62E, sCD14, sCD163, and FABP2
• Dataset is openly licensed under CC-BY-4.0

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset is small in scale at 80.5 KB, indicating limited scope

Provenance

Source

Saroj Chandra Lohani via figshare

Collection Method

Experimental study using a double humanized-BLT mouse model, with multi-omics analysis.

Freshness

Last updated 2026-06-03 04:47:37; freshness should be verified