Genomic Characterization of Respiratory Elizabethkingia Isolates, 2024–2025

18 Elizabethkingia isolates from 16 patients at a tertiary pulmonary hospital were analyzed via whole-genome sequencing and antimicrobial susceptibility testing. Yongpeng Shang authored this study, which was published on figshare in April 2026. The data includes species identification, pangenome analysis, phylogenetic reconstruction, and molecular docking results for fluoroquinolone resistance.

Use Cases

• Analyzing clade-specific clustering and potential nosocomial transmission based on core-genome phylogeny
• Investigating fluoroquinolone non-susceptibility mechanisms based on mutations in the quinolone resistance-determining region (QRDR)
• Evaluating antimicrobial resistance profiles across multiple drug classes based on VITEK® 2 susceptibility testing results
• Studying the structural impact of the GyrA S83I substitution on drug binding affinity based on molecular docking analysis

Strengths

• 18 non-duplicate isolates from 16 patients provide a focused clinical cohort
• Data includes whole-genome sequencing, pangenome analysis, and molecular docking for integrated findings
• All isolates underwent antimicrobial susceptibility testing with a standardized VITEK® 2 system

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data may reflect temporal and institutional bias inherent to a single tertiary hospital study from 2024–2025

Provenance

Source

Yongpeng Shang

Collection Method

Whole-genome sequencing and antimicrobial susceptibility testing performed on clinical isolates.

Time Range

2024–2025

Freshness

Last updated 2026-04-10 06:03:21

Geography

Isolates collected from a tertiary pulmonary hospital; specific location unknown.