DTI-ALPS Index Meta-Analysis for Glymphatic Function in Type 2 Diabetes

Seven studies comprising 532 participants were synthesized in a systematic review and meta-analysis comparing DTI-ALPS indices between individuals with type 2 diabetes mellitus (T2DM) and healthy controls. The dataset, authored by Yaxi Chen and published on figshare in May 2026, contains pooled effect sizes (Hedges' g) for subgroups of uncomplicated and complicated T2DM.

Use Cases

• Comparing glymphatic function between diabetic and healthy cohorts based on DTI-ALPS index meta-analysis
• Investigating the association between diabetes complications and perivascular water diffusivity based on subgroup analyses
• Evaluating heterogeneity and statistical significance in neuroimaging meta-analyses based on reported I² and p-values

Strengths

• Includes data from 532 participants across seven studies
• Provides subgroup analyses distinguishing uncomplicated and complicated T2DM phenotypes
• Reports pooled Hedges' g effect sizes with confidence intervals and heterogeneity metrics (I²)

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is a PDF file of 456.3 KB, which suggests a limited scope and may require manual data extraction

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published DTI-ALPS studies

Freshness

Last updated 2026-05-21 05:42:30; freshness should be verified