Immune Correlates of Vaccine-Associated Small Fiber Neuropathy in 71 Patients

71 previously healthy patients with neurological symptoms following SARS-CoV-2 vaccination were studied. Alessandro Limongelli published data on symptom onset, severity, and immune markers like anti-ACE-2 antibodies and NKG2D+ T-cells. The dataset was last updated on March 19, 2026.

Use Cases

• Analyze symptom onset timing based on median time from vaccination to manifestation
• Correlate immune markers like NKG2D+CD8+ T-cells with symptom severity scores
• Compare small fiber density from biopsies with patient-reported autonomic symptoms
• Investigate antibody reactivity patterns (anti-ACE-2, NRP-1) across patient and control sera

Strengths

• Includes data from 71 patients with detailed clinical and immunological assessments
• Provides specific metrics like median symptom onset time (3 days) and symptom severity (5.9 ± 1.9)
• Contains results from 21 cutaneous biopsies and peripheral blood sampling from 20 patients

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 101.7 KB file size suggests a limited scope of data

Provenance

Source

figshare

Collection Method

Clinical study involving patient workup, biopsies, and blood sampling for ELISA, IF, and flowcytometric analysis.

Freshness

Last updated 2026-03-19 05:19:28