Data Sheet 2_Interleukin-15 correlates with cytotoxic immune networks in cervical tubercul

A clinical study profiling immune responses in patients with cervical tuberculous lymphadenitis (CTL). The dataset includes integrated immune profiling of 60 CTL patients and 44 non-tuberculous control patients, with measurements from peripheral blood and lymph node mononuclear cells. It was authored by Soumaha Bchiri and last updated on June 3, 2026.

Use Cases

• Identify hub cytokines in immune networks based on correlation-network analysis described in the study.
• Correlate cytokine levels with bacterial burden based on GeneXpert-defined bacillary load.
• Analyze tissue-specific immune signatures based on immunohistochemistry data for IL-15 and IL-15Rα.
• Compare cytotoxic immune program expression between patient cohorts based on granulysin, granzyme B, and perforin levels.

Strengths

• Includes data from 104 total patients (60 CTL, 44 CNTL).
• Integrates multiple data types: qPCR gene expression, ELISA serum cytokine measurement, and immunohistochemistry.
• Strong statistical significance reported for key findings (e.g., p < 0.0001 for circulating IL-15).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 7.7 MB file size suggests a small dataset, potentially limiting statistical power for complex analyses.

Provenance

Source

figshare

Collection Method

Integrated immune profiling via qPCR, ELISA, and immunohistochemistry on patient samples.

Freshness

Last updated 2026-06-03 04:47:34; freshness should be verified.