LGMN Gene Signature and Cell Interaction Data for Idiopathic Pulmonary Fibrosis

A 33.1 KB CSV file from figshare, last updated April 13, 2026, by author Yuechong Xia. It contains data supporting a study on macrophage-related gene signatures in idiopathic pulmonary fibrosis (IPF). The data was derived from single-cell transcriptomic and microarray analyses sourced from the GEO database.

Use Cases

• Developing a prognostic gene signature for IPF patients based on monocyte-derived macrophage (MDM) genes.
• Analyzing cell-cell interactions, particularly between macrophages and fibroblasts, using inferred interaction data.
• Investigating the role of the LGMN gene and TGF-β1 signaling pathway in fibrosis progression.
• Validating potential therapeutic targets, such as LGMN inhibition, for pulmonary fibrosis treatment.

Strengths

• Data is derived from single-cell transcriptomic and microarray sources, suggesting high-resolution biological detail.
• The study methodology includes validation via ROC curves and an external dataset, indicating a structured analytical approach.
• Released under a CC-BY-4.0 license, permitting open reuse and modification.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is very small at 33.1 KB, indicating limited scope, likely containing summary or processed results rather than raw sequencing data.
• Description metadata is limited; actual data structure and field semantics must be inferred after download.

Provenance

Source

figshare, author Yuechong Xia.

Collection Method

Analyzed from single-cell transcriptomic and microarray data sourced from the GEO database.

Time Range

Temporal coverage of the underlying patient data is not specified.

Freshness

Last updated 2026-04-13 04:35:55; freshness should be verified.

Geography

Spatial coverage is not specified.