Influenza Virus Genomes from a Pediatric Hospital in Eastern China, 2024

425 influenza virus genomes were sequenced from 490 antigen-positive specimens collected in 2024 from a pediatric hospital in Qidong, eastern China. The dataset includes A/H1N1, A/H3N2, and B/Victoria lineages, with phylogenetic clade assignments and analysis of antiviral resistance markers. The research was authored by Xiaoqing Sun and published on figshare in 2026.

Use Cases

• Phylogenetic analysis of influenza clade circulation based on the described 6B.1A.5a.2a, 3C.2a1b.2a.2a.3a.1, and V1A.3a.2 assignments.
• Monitoring antiviral resistance trends based on the detected oseltamivir resistance marker NA-H275Y in A/H1N1 strains.
• Studying positive selection in viral proteins based on the identified lineage-specific sites in hemagglutinin.
• Analyzing seasonal co-circulation patterns of influenza subtypes based on the described activity peaks and prevalence percentages.

Strengths

• Sequencing yielded 425 genomes from 490 specimens, an 86.73% success rate for at least HA and NA segments.
• Includes specific clade assignments and prevalence data for A/H1N1 (45.41%), A/H3N2 (18.35%), and B/Victoria (36.24%).
• Reports concrete antiviral resistance findings, including the NA-H275Y marker in 7/193 (3.65%) A/H1N1 strains.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is from a single pediatric hospital in one city, which may limit geographic generalizability.

Provenance

Source

Xiaoqing Sun via figshare.

Collection Method

Influenza genome enrichment-based whole-genome sequencing performed on clinical specimens.

Time Range

2024

Freshness

Last updated 2026-04-16 05:22:46; freshness should be verified.

Geography

Qidong, eastern China.