Data Sheet 2_Multi-layer transcriptomic analyses identify a mucin-associated epithelial pr

Data Sheet 2 from figshare contains transcriptomic data analyzed in a study linking mucin-associated epithelial programs to inflammatory injury in ulcerative colitis. The dataset likely contains bulk, single-cell, and spatial transcriptomic analyses from the discovery cohort GSE107499. It was authored by Jianmin Huang and last updated on June 3, 2026.

Use Cases

• Identify dysregulated mucin-type O-glycosylation genes based on transcriptomic analyses
• Associate GALNT12 expression with inflammatory pathway enrichment based on the description
• Analyze epithelial cell communication networks based on inferred single-cell resolution data
• Correlate spatial transcriptomic niches with goblet cell signatures and inflammatory scores

Strengths

• Integrates multi-layer transcriptomic analyses (bulk, single-cell, spatial) as described
• Focuses on 15 dysregulated mucin-type O-glycosylation and mucin-associated genes identified in the discovery cohort
• Includes functional validation experiments (e.g., GALNT12 knockdown in HT29-19A cells) referenced in the study

Limitations

• Dataset size is 481.6 KB, indicating a limited scope of data
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Likely contains processed transcriptomic data from the study's discovery cohort GSE107499 and subsequent analyses.

Freshness

Last updated 2026-06-03 04:47:33; freshness should be verified