18F-Fluciclovine PET Background Uptake in Head Tissues for Glioma Assessment

20 patients with suspected malignant glioma underwent 18F-fluciclovine PET/CT imaging to establish a baseline for physiological tracer uptake. The study measured standardized uptake values in 24 predefined head regions and compared them with 11C-methionine PET in a subset of 8 patients. Yumi Abe published this data on figshare in 2026 to aid in distinguishing normal from pathological uptake in brain tumor evaluation.

Use Cases

• Establishing a normal reference range for 18F-fluciclovine PET based on SUV measurements in 24 head regions.
• Comparing tracer uptake patterns between 18F-fluciclovine and 11C-methionine for brain tumor imaging.
• Analyzing temporal uptake dynamics in structures like the pituitary and parotid glands based on time–activity curves.
• Training or validating AI models for automated segmentation of physiological vs. tumor uptake in PET scans.

Strengths

• Includes data from 20 patients, providing a defined cohort size.
• Measures standardized uptake values in 24 predefined anatomical regions, enabling structured analysis.
• Contains comparative data from 8 patients who also underwent 11C-methionine PET/CT.
• Provides specific quantitative results, such as a white matter SUVmean of 0.15 ± 0.04.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (369.2 KB), indicating limited scope, likely containing summary results rather than raw image data.

Provenance

Source

figshare, author Yumi Abe.

Collection Method

Retrospective analysis of 18F-fluciclovine PET/CT images from patients with suspected malignant glioma.

Freshness

Last updated 2026-06-02 05:40:37; freshness should be verified.