Parkinson's Disease Trial Data: Qihuang Needle Therapy Efficacy and MRI Neuroplasticity

A clinical trial protocol for a triple-arm randomized controlled trial investigating Qihuang needle therapy for Parkinson's disease. The dataset includes clinical outcomes and multimodal MRI neuroplasticity markers from 69 patients. The protocol was authored by Wanqing Peng and uploaded to figshare in April 2026.

Use Cases

• Analyze the efficacy of a novel acupuncture technique based on Unified Parkinson's Disease Rating Scale (UPDRS-III) scores.
• Investigate neuroplasticity mechanisms based on multimodal MRI markers like gray matter volume and functional connectivity.
• Compare treatment effects across verum acupuncture, sham acupuncture, and wait-list control groups.
• Correlate clinical symptom changes with neuroimaging biomarkers like nigral iron deposition and neuromelanin content.

Strengths

• Data is from a triple-arm randomized controlled trial, a rigorous study design.
• Includes multimodal MRI markers for neuroplasticity, such as gray matter volume and white matter integrity.
• Clinical outcomes are measured with standardized scales like UPDRS-III, NMSS, and PDQ-39.
• The protocol is openly licensed under CC-BY-4.0.

Limitations

• The dataset is a 144.5 KB PDF protocol document; the underlying clinical and imaging data are not directly available.
• Row count and column-level documentation for the actual trial data are unknown.
• The data is scheduled for collection in a future trial; results are not yet included.

Provenance

Source

figshare

Collection Method

Data described is to be collected via a randomized controlled trial.

Time Range

Trial protocol published in 2026; temporal coverage of future data collection is unspecified.

Freshness

Last updated 2026-04 -13 13:15:22; freshness should be verified.

Geography

Geographic coverage of patient enrollment is unspecified.