Body Roundness Index Meta-Analysis: Risk Association for CKM Outcomes

A systematic review and meta-analysis of 93 observational studies from 13 countries, investigating the association between the body roundness index (BRI) and cardiovascular-kidney-metabolic (CKM) syndrome outcomes. The study was authored by Hongjia Fu and published on figshare in April 2026. It pools effect sizes from literature up to July 7, 2025, and includes a diagnostic meta-analysis.

Use Cases

• Evaluating the diagnostic performance of BRI for metabolic syndrome based on the reported discriminatory ability.
• Comparing risk associations of BRI across different CKM outcomes (e.g., chronic kidney disease, cardiovascular disease) as described in the results.
• Assessing gender-specific differences in BRI risk associations for CKM outcomes as mentioned in the subgroup analysis.
• Informing clinical tool development for visceral fat assessment based on the review's conclusion about BRI's incremental information.

Strengths

• Analysis is based on 93 included studies, providing a substantial evidence base.
• Literature search was comprehensive across PubMed, Web of Science, and Embase.
• Study protocol is registered with PROSPERO (CRD420251110973), indicating structured methodology.
• Includes a diagnostic meta-analysis component to assess discriminatory ability.

Limitations

• The dataset is a 30.5 KB DOCX file containing the review manuscript, not the underlying primary data.
• Row count and column-level documentation for any extracted data are unknown.
• The findings are constrained by the quality and heterogeneity of the included observational studies.

Provenance

Source

figshare

Collection Method

Systematic literature review and meta-analysis of published observational studies.

Time Range

Literature search updated to July 7, 2025.

Freshness

Last updated 2026-04-14 05:10:25; literature search updated to July 7, 2025.

Geography

Studies involved 13 countries (specific countries not listed).