Data Sheet 2_Safety and efficacy of completely transthoracic echocardiography guided leadless pacemaker implantation assisted by Panna guide wire: initial clinical experience.pdf

10 patients underwent completely fluoroscopy-free leadless pacemaker implantation guided by transthoracic echocardiography and the Panna guidewire. The study compares this cohort against a historical control group of 44 fluoroscopy-guided patients, with data on procedural duration, safety endpoints, and pacing parameters. Results from this initial clinical experience show 100% procedural success and no adverse events over a median 4.7-month follow-up.

Use Cases

• Compare procedural duration between TTE-guided and fluoroscopy-guided cohorts to assess efficiency.
• Analyze safety endpoints and adverse event rates across patient groups.
• Evaluate pacing parameter stability in the TTE-guided cohort during follow-up.
• Assess the impact of preoperative TTE acoustic window grading on procedural success.

Strengths

• Includes a comparative analysis with a propensity score-weighted control group of 44 patients.
• All safety and efficacy endpoints were formally predefined prior to patient enrollment.
• Procedural success was 100% with no adverse events in the TTE-guided cohort.

Limitations

• Small sample size of 10 patients in the TTE-guided intervention group.
• Long-term follow-up data (12/24 months) is incomplete and ongoing.
• Data is contained within a single PDF document, limiting direct computational analysis.

Provenance

Source

Qiuzhe Guo

Collection Method

Prospectively protocolized, single-arm design for the TTE-guided cohort with retrospective comparative analysis against a historical control group.

Time Range

TTE-guided cohort: July 2024–July 2025; Control group: January 2020–December 2023.

Freshness

Data covers a study period from July 2024 to July 2025, with the resource last updated in March 2026.

Geography

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