Stress, Gut Microbiota, and Metabolite Data for Hepatocellular Carcinoma Progression

A figshare-hosted dataset from a study investigating how stress accelerates hepatocellular carcinoma progression via a gut microbial-metabolite axis. The dataset, authored by Zhe Hu and last updated in May 2026, integrates clinical and preclinical models to examine microbial restructuring and the role of the metabolite indole-3-propionic acid. Its findings suggest potential microbiome-based therapeutic targets for liver cancer.

Use Cases

• Modeling hepatocellular carcinoma progression based on stress and gut microbial profiles
• Investigating the role of the metabolite indole-3-propionic acid in tumor suppression
• Analyzing endothelial-macrophage crosstalk in the tumor microenvironment based on JAM2-F11R interactions
• Exploring microbiome-based therapeutic strategies for liver cancer

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• The study integrates clinical and preclinical models, suggesting a multi-faceted data collection approach.

Limitations

• The dataset is very small at 47.9 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Integrating clinical and preclinical models, with in vitro and in vivo interrogations of the tumor microenvironment.

Freshness

Last updated 2026-05-12 16:10:01; freshness should be verified.