100 differentially expressed miRNAs were identified in Duchenne muscular dystrophy muscle tissue. Yayu Wang published this dataset on figshare in May 2026. It likely contains results from integrated RNA-seq analyses of GSE38417, GSE109178, GSE157668, and GSE213925 datasets.
Use Cases
- Validate miRNA-mRNA regulatory axes based on differential expression analysis results.
- Investigate inflammatory pathway enrichment in SOCS3+ cells based on single-cell RNA-seq findings.
- Model metabolic process suppression in DMD muscle based on pathway analysis.
- Benchmark SOCS3 expression levels in mdx mice based on transcriptional and translational data.
- Assess anti-inflammatory effects of miR-30c-5p restoration based on TNF-α and IL-10 level changes.
Strengths
- Integrated analysis of four distinct public RNA-seq datasets (GSE38417, GSE109178, GSE157668, GSE213925).
- Functional validation results from experiments in mdx mice, C2C12 myoblasts, and primary skeletal muscle cells.
- Data is openly licensed under CC-BY-4.0.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset is very small (1.8 KB), suggesting limited scope.
Provenance
- Source
- figshare
- Collection Method
- Integrated bulk RNA-seq, small RNA-seq, and single-cell RNA-seq data from public repositories.
- Freshness
- Last updated 2026-05-22 05:35:35; freshness should be verified.