ANCA-Associated Vasculitis Patient Biomarker Data from China

Yunan Li's research dataset contains clinical records for 532 patients first diagnosed with ANCA-associated vasculitis at Tianjin Medical University General Hospital between June 2012 and June 2024. It investigates the neutrophil-to-lymphocyte ratio (NLR) as a biomarker for associations with organ involvement, all-cause mortality, and end-stage renal disease.

Use Cases

• Analyze the nonlinear relationship between the neutrophil-to-lymphocyte ratio (NLR) and all-cause mortality using restricted cubic spline methods.
• Assess NLR association with the presence of fever and renal dysfunction at diagnosis via logistic regression.
• Perform Kaplan-Meier survival analysis to compare mortality risk between high NLR (>10) and low NLR patient groups.
• Conduct subgroup analysis on infection-related mortality proportions across different NLR levels.

Strengths

• Dataset includes 532 patient records from a single hospital cohort.
• Clinical analysis covers a 12-year time range from June 2012 to June 2024.
• Study employs multiple statistical methods: logistic regression, Cox regression, Kaplan-Meier, and ROC analysis.

Limitations

• Data is presented only in a 112.4 KB PDF report; underlying tabular data is unavailable.
• Sample is from a single hospital in China, limiting geographic generalizability.
• Retrospective study design may introduce selection bias.

Provenance

Source

Yunan Li via figshare.

Collection Method

Retrospective study of hospital patient records.

Time Range

June 2012 to June 2024.

Freshness

Last updated March 2026.

Geography

Tianjin Medical University General Hospital, China.