Clinical Features and Mortality in Intestinal Ulceration with Pancytopenia, 128 Patients

128 patient records from a pooled individual-patient data systematic review characterize the rare condition of intestinal ulceration with pancytopenia. The dataset, created by Song Su and last updated in May 2026, includes clinical features, mortality outcomes, and prognostic factors from 60 studies. Overall mortality was substantial, ranging from 31.3% to 44.4% across patient subgroups.

Use Cases

• Analyze mortality risk factors based on reported associations with sex and MDS evolution.
• Compare clinical feature patterns, such as ulcer location and trisomy 8 prevalence, between disease subgroups.
• Study the temporal relationship between intestinal symptom onset and hematologic disease diagnosis.
• Benchmark survival outcomes for high-risk MDS subtypes in patients with concurrent inflammatory bowel disease.

Strengths

• Data is pooled from 60 studies, providing a synthesis of rare case evidence.
• Includes specific mortality rates (31.3% to 44.4%) and patient counts (128) for key analyses.
• Systematic review methodology is documented with a PROSPERO registration identifier (CRD42020165205).

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is very small (16.4 KB), indicating limited scope and a focus on aggregated summary data.
• Data may reflect publication bias inherent to systematic reviews of case reports and series.

Provenance

Source

Systematic review of PubMed, Embase, ClinicalTrials.gov, and PROSPERO up to November 10, 2025.

Collection Method

Pooled individual-patient data analysis from eligible case reports, case series, and cohort studies.

Time Range

Database inception to November 10, 2025.

Freshness

Last updated 2026-05-29 06:13:22