Genomic Atlas of Gut Clostridia: Phylogeny and Short-Chain Fatty Acid Production

A 2026 study by Laura Sola provides a taxonomic reclassification and functional analysis of 1,897 gut Clostridia species. The dataset includes results from phylogenetic analysis and the identification of 519 potential butyrate producers and 257 potential propionate producers. The analysis is based on genomes from the Unified Human Gastrointestinal Genome database and includes profiling from 151 faecal metagenomes of healthy subjects.

Use Cases

• Classifying gut microbial species based on phylogenetic relationships described in the study
• Identifying potential butyrate and propionate producers based on biosynthetic pathway analysis
• Assessing the relative abundance of specific Clostridia species in healthy human microbiomes

Strengths

• Includes analysis of 1,897 Clostridia species, with 404 having recognized taxonomic classification
• Identifies 519 species as potential butyrate producers and 257 as potential propionate producers
• Profiles species abundance using 151 faecal metagenomes from healthy subjects

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

Laura Sola via figshare

Collection Method

Genomic reclassification using GTDB-Tk and functional analysis with GapSeq on genomes from the Unified Human Gastrointestinal Genome database

Time Range

Study published in 2026

Freshness

Last updated 2026-04-10 05:59:10; freshness should be verified

Geography

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