Oxytocin Levels and IVF Live Birth Rates: A Prospective Cohort Study

680 infertile patients undergoing IVF cycles between October 2024 and January 2025 were enrolled for serum and follicular fluid oxytocin measurement. The prospective cohort study, authored by Ruiqiong Zhou, investigates associations between these hormone levels and live birth rates using multiple statistical models. Results indicate a negative linear association for serum oxytocin and a positive association for follicular fluid oxytocin with live birth outcomes.

Use Cases

• Predicting IVF success likelihood based on pre-stimulation serum oxytocin levels mentioned in the study
• Analyzing correlations between follicular fluid oxytocin and ovarian response markers like hCG-trigger day estradiol
• Modeling the relationship between hormone levels and clinical parameters such as triglycerides, LDL-C, and insulin
• Validating statistical approaches like inverse probability weighting for clinical cohort data analysis

Strengths

• Data from 680 patients provides a substantive cohort for analysis.
• Study employed three statistical approaches (multivariable logistic regression, inverse probability weighting, double robust model) for robust association testing.
• Specific effect sizes are reported, such as a 37% decrease in live birth likelihood per 100 pg/mL serum oxytocin increase.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (17.8 KB), indicating limited scope, likely containing summary results rather than raw patient-level data.

Provenance

Source

Ruiqiong Zhou via figshare

Collection Method

Prospective cohort study of patients undergoing IVF cycles.

Time Range

October 2024 to January 2025

Freshness

Last updated 2026-06-02 04:21:28; freshness should be verified.