Epimedium Effects on Alzheimer's Disease: Neuroinflammation and KAT2B Expression Data

Data Sheet 3 contains experimental results from a study on Epimedium's effects on Alzheimer's disease. The dataset, authored by Jie Gao and last updated on April 20, 2026, includes findings from in vivo studies on rats, such as cognitive function assessments and molecular expression levels. It is a 12.3 KB Excel file shared under a CC-BY-4.0 license on figshare.

Use Cases

• Analyzing the relationship between KAT2B expression and cognitive deficits based on the described qRT-PCR results.
• Modeling the effect of Epimedium on neuroinflammatory markers like IL-1β and TNF-α based on ELISA data mentioned in the description.
• Investigating the correlation between histopathological damage in hippocampal neurons and behavioral test scores based on the Morris water maze and H&E staining results.

Strengths

• Dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• The study design is described in detail, including the use of an AD model established with AlCl3 and D-galactose.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 12.3 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Data generated from laboratory experiments on rats, including behavioral tests (Morris water maze), histopathology (H&E staining), and molecular assays (ELISA, qRT-PCR).

Time Range

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Freshness

Last updated 2026-04-20 04:12:08; freshness should be verified.

Geography

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