Millettia Speciosa Proteomic Data from an Allergic Asthma Mouse Model

A proteomic analysis from a study investigating the therapeutic effects of Niudali (Millettia speciosa) in an ovalbumin-induced mouse model of allergic asthma. The dataset includes results from high-resolution data-independent acquisition (DIA) lung proteomics and cytokine profiling, identifying 179 differentially expressed proteins. The data was authored by Hangrui Yang and last updated on 2026-06-03.

Use Cases

• Identify potential drug targets for asthma based on the 179 differentially expressed proteins.
• Study the role of the CCL24-eosinophil axis in allergic inflammation based on the described suppression.
• Analyze immunometabolic pathway modulation based on the described enrichment in complement, coagulation, lipid transport, and PPAR signaling.
• Investigate hub proteins in asthma pathology based on the identified key proteins Alb, Apoe, Apoa1, Proc, and Serpina7.

Strengths

• Identifies 179 differentially expressed proteins, providing a specific molecular signature.
• Integrates proteomic data with cytokine profiling (IgE, IL-4, IL-5, IL-6) for validation.
• Data is openly shared under a CC-BY-4.0 license.

Limitations

• The dataset is very small at 4.4 KB, suggesting limited raw data or summary-level results only.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.

Provenance

Source

figshare

Collection Method

High-resolution data-independent acquisition (DIA) lung proteomics integrated with cytokine profiling from an ovalbumin-induced mouse model.

Freshness

Last updated 2026-06-03 07:42:22; freshness should be verified.