Influenza Virus Genomes from a Pediatric Hospital in Eastern China, 2024

Xiaoqing Sun sequenced 425 influenza genomes from 490 pediatric specimens collected in Qidong, eastern China, in 2024. The data includes co-circulation patterns of A/H1N1, A/H3N2, and B/Victoria lineages, phylogenetic clade assignments, and antiviral resistance markers. The findings were published in 2026 to support local genomic surveillance and clinical management.

Use Cases

• Modeling influenza strain co-circulation patterns based on the reported prevalence of A/H1N1, A/H3N2, and B/Victoria.
• Tracking genetic evolution and phylogenetic clade assignment based on the described HA and NA segment sequences.
• Monitoring antiviral resistance based on the detected oseltamivir resistance marker NA-H275Y in A/H1N1 strains.
• Analyzing seasonality and activity peaks based on the reported circulation peaks in January and December.

Strengths

• Includes 425 complete or partial influenza genomes from a specific pediatric population.
• Reports specific prevalence percentages for three co-circulating lineages: A/H1N1 (45.41%), A/H3N2 (18.35%), and B/Victoria (36.24%).
• Identifies specific phylogenetic clades and positively selected sites in the hemagglutinin (HA) protein.
• Quantifies the presence of the oseltamivir resistance marker NA-H275Y in 7 out of 193 A/H1N1 strains.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• Data is limited to a single pediatric hospital in Qidong, China, in 2024, which may limit generalizability.
• The dataset is very small (46.4 KB), suggesting limited scope, likely containing summary results rather than raw sequence data.

Provenance

Source

Author: Xiaoqing Sun. Platform: figshare.

Collection Method

Influenza genome enrichment-based whole-genome sequencing performed on antigen-positive pediatric specimens.

Time Range

2024

Freshness

Last updated 2026-04-16 05:22:46; freshness should be verified.

Geography

Qidong, eastern China