N-acyl-homoserine Lactone Quorum Sensing Data from Underexplored Bacterial Lineages

A 48.9 KB Excel file by Christy R. Handel, last updated April 2026, contains data from a study investigating N-acyl-homoserine lactone-based quorum sensing in underexplored bacterial lineages. The research analyzed four bacterial strains from Hawai'i and the Bahamas, using custom HMMs, LC-MRM-MS, and targeted gene disruption to identify and characterize putative luxI/R homologs.

Use Cases

• Comparative genomic analysis of luxI/R homologs based on the described phylogenetic and domain architecture findings.
• Modeling the ecological roles of AHL signaling in Actinomycetota based on the described association with metabolism and redox genes.
• Training classifiers to identify non-canonical quorum sensing systems based on the described genomic context and protein architecture features.

Strengths

• Data is derived from a specific, peer-reviewed research methodology including LC-MRM-MS and targeted gene disruption.
• Focuses on underexplored bacterial lineages and environments, expanding beyond canonical Pseudomonadota models.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset's 48.9 KB size suggests a limited scope, likely containing summary or processed results rather than raw sequencing data.

Provenance

Source

figshare

Collection Method

Custom hidden Markov model identification, liquid chromatography-mass spectrometry, and genomic analysis of bacterial strains.

Time Range

null

Freshness

Last updated 2026-04-20 05:20:48; freshness should be verified.

Geography

Includes samples from Hawai'i (taro lo‘i, lava cave) and San Salvador Island, Bahamas (hypersaline mat).