N-acyl-homoserine Lactone Quorum Sensing Data from Underexplored Bacterial Lineages

A dataset from a study investigating N-acyl homoserine lactone-based quorum sensing in bacteria from underexplored environments, including newly described species. The data, created by Christy R. Handel and last updated in May 2026, likely contains results from genomic analyses and mass spectrometry. It focuses on expanding the known diversity of AHL-QS systems beyond the canonical Pseudomonadota model.

Use Cases

• Phylogenetic analysis of luxI/R-family proteins based on the described protein phylogeny.
• Comparative genomics to study the genomic context of luxI genes in Actinomycetota.
• Validating AHL production using mass spectrometry data mentioned in the description.
• Investigating regulatory domain architecture in LuxR-family proteins based on the described helix-turn-helix structures.

Strengths

• Data is derived from a specific study using custom hidden Markov models (HMMs) and liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS).
• Includes analysis of bacteria from distinct, underexplored environments like a taro lo‘i in Hawai‘i and a lava cave.
• License is CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset is small (48.9 KB), indicating limited scope.
• Description metadata is detailed but actual data structure must be inspected after download.

Provenance

Source

figshare, author Christy R. Handel

Collection Method

Custom HMMs for gene identification, genomic context analysis, protein phylogeny, LC-MRM-MS for AHL detection, and targeted gene disruption.

Freshness

Last updated 2026-05-08 17:27:22

Geography

Samples from Hawai‘i (taro lo‘i, lava cave) and San Salvador Island, Bahamas (hypersaline mat); also includes a culture-derived sample.