Quadrupedal Training Evidence Review for Post-Stroke Rehabilitation

Eighteen studies, including five randomized controlled trials, were synthesized in this 2025 scoping review on quadrupedal-derived training for adults after stroke. Jan A. Kuipers authored this review, which maps evidence, mechanisms, and clinical applications from literature published between 2010 and 2025. The document is a 18.5 KB summary of findings.

Use Cases

• Analyze intervention types and total dosage data to compare the clinical application of different quadrupedal training variants.
• Map study outcomes to International Classification of Functioning (ICF) domains for a structured review of functional improvements.
• Review safety and feasibility data, including recorded adherence rates and absence of serious adverse events, for clinical risk assessment.
• Examine mechanistic evidence pathways linking quadrupedal loading to activation of spinal networks and bilateral proximal muscles.
• Compare balance benefits of kneeling-based QT versus treadmill-based training using results from subacute inpatient settings.

Strengths

• Synthesizes evidence from 18 identified studies, including 5 randomized controlled trials.
• Follows JBI and PRISMA-ScR guidelines for systematic scoping review methodology.
• Incorporates stakeholder input from stroke survivors, clinicians, and researchers for implementation considerations.
• Covers literature from a 15-year time range (2010 to 2025).

Limitations

• The dataset is a summary document (18.5 KB), not the underlying raw study data, limiting direct analysis.
• Sample size for the included human studies is not provided, preventing assessment of evidence scale.
• Conclusions highlight a need for more well-designed studies, indicating current evidence is not definitive.

Provenance

Source

figshare, authored by Jan A. Kuipers.

Collection Method

Scoping review conducted via systematic search of five databases and additional sources.

Time Range

2010 to 2025

Freshness

Literature review covers up to 2025; document last updated April 2026.

Geography

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