Planarian Behavioral Screening Data for 21 Organophosphorus Pesticide Mixtures

21 binary mixtures of 7 organophosphorus pesticides were screened in adult and regenerating Dugesia japonica planarians. The dataset includes 22 readouts quantifying lethality, stickiness, and behavior on days 7 and 12 post-exposure, with comparisons to a Loewe concentration addition model. It was authored by Danielle Ireland and last updated on 2026-03-25.

Use Cases

• Modeling additive and non-additive chemical interactions based on the 22 behavioral and lethality readouts.
• Comparing neurotoxic effects on adult versus developing nervous systems based on the screening of regenerating planarians.
• Correlating behavioral outcomes like stickiness with acetylcholinesterase inhibition data for select mixtures.
• Validating high-throughput screening platforms for organophosphorus pesticide toxicity using the planarian model system.

Strengths

• Includes data for 21 binary mixtures of 7 distinct organophosphorus pesticides.
• Provides 22 automated readouts per mixture, covering lethality, stickiness, and behavior.
• Compares experimental results to a formal Loewe concentration addition model for interaction assessment.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 26.7 KB, indicating limited scope.

Provenance

Source

Danielle Ireland via figshare

Collection Method

Experimental screening using an automated platform on adult and regenerating Dugesia japonica planarians.

Freshness

Last updated 2026-03-25 22:02:15; freshness should be verified.