Serum Progesterone Levels for Rescue in Hormone Replacement FET: 917 Cycles (2017-2023)

A single-center retrospective cohort study of 917 hormone replacement frozen embryo transfer (HRT-FET) cycles from 2017 to 2023. The dataset, authored by Goksu Goc and shared under CC-BY-4.0, compares outcomes for patients grouped by receipt of a single-dose progesterone rescue injection, with pre-transfer progesterone levels measured by Cobas e411 ECLIA. It explores the association between very low pre-transfer progesterone levels and live birth rates.

Use Cases

• Analyzing the relationship between pre-transfer progesterone levels and live birth rates based on the stratified groups (<5, 5–7.49, 7.5–9.99 ng/mL).
• Investigating miscarriage rates among clinical pregnancies based on pre-transfer progesterone thresholds.
• Evaluating the performance of a single 50 mg intramuscular progesterone rescue protocol for different patient subgroups.
• Exploring the predictive value of pre-transfer progesterone levels using ROC analysis and bootstrap resampling methods mentioned in the description.

Strengths

• Includes data from 917 HRT-FET cycles, providing a substantial clinical cohort.
• Stratifies the 267 Rescue group patients into three pre-transfer progesterone ranges for detailed analysis.
• Employs multiple statistical analyses including multivariable logistic regression and bootstrap resampling as described.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The study is single-center and retrospective, which may limit generalizability.

Provenance

Source

figshare, authored by Goksu Goc.

Collection Method

Single-center retrospective cohort study.

Time Range

2017–2023

Freshness

Last updated 2026-06-01 04:17:41; freshness should be verified.