Measles Virus MF-NCR Phylogenetic Profiles for Genotypes B3, D4, D8, H1

A phylogenetic analysis of the measles virus MF-non-coding region across four genotypes (B3, D4, D8, H1) from different locations and collection periods. The study, authored by Matteo Fracella and published on figshare in 2026, reports variable site proportions ranging from 13.4% for genotype D4 to 47% for genotype D8. It provides insights into evolutionary dynamics and genetic diversity before the COVID-19 pandemic.

Use Cases

• Phylogenetic clustering analysis based on genotype and location data mentioned in the description
• Estimating evolutionary divergence and sequence variability across measles virus genotypes
• Studying the link between the MF-NCR region and viral cytopathogenicity or protein expression

Strengths

• Analysis covers four major measles virus genotypes (B3, D4, D8, H1) prevalent before the COVID-19 pandemic
• Provides specific variability metrics, such as 47% variable sites for genotype D8
• Includes data from multiple locations and collection periods for intermixing analysis

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data is presented in a 161.1 KB PDF, which may require extraction for computational analysis

Provenance

Source

figshare

Collection Method

Maximum likelihood phylogenetic analysis performed using Phyml, with evolutionary divergence estimated using MEGA X.

Time Range

Collection periods before the COVID-19 pandemic (specific years not provided).

Freshness

Last updated 2026-05-08 05:54:20; freshness should be verified

Geography

Different locations (specific regions not provided).