Meta-Analysis of Fermented Food Consumption and Mortality Risk from 50 Cohort Studies

A meta-analysis document aggregating evidence from 50 prospective cohort studies involving over three million participants. It was authored by Antonia Matalas and last updated in March 2026. The study evaluates associations between fermented food intake and all-cause, cardiovascular disease, and cancer mortality.

Use Cases

• Conducting secondary analysis on the protective effects of chocolate, cheese, and fermented milks based on the aggregated risk estimates.
• Evaluating methodological approaches for meta-analyses of cohort studies based on the described DerSimonian and Laird method.
• Investigating the role of bioactive compounds from fermented foods in modulating gut microbiota based on the conclusions discussed.
• Comparing associations between different fermented foods (e.g., miso, bread) and mortality outcomes based on the reported results.

Strengths

• Systematic review protocol is registered and publicly accessible (OSF identifier: vg7f6).
• Analysis synthesizes data from 50 cohort studies with over three million participants.
• Risk of bias was formally assessed using the Newcastle-Ottawa Scale.

Limitations

• The primary data file is a 304.2 KB DOCX document; the underlying tabular data (e.g., effect sizes, confidence intervals) is not directly provided in a machine-readable format.
• Column-level documentation for any extracted study data is absent; field semantics must be inferred from the manuscript.
• Row count for any underlying data tables is unknown, which may limit suitability assessment for direct computational analysis.

Provenance

Source

Antonia Matalas via figshare

Collection Method

Systematic review and meta-analysis of published prospective cohort studies.

Time Range

Temporal coverage of the included primary studies is not specified.

Freshness

Last updated 2026-03-18 07:41:04

Geography

Geographic coverage of the included primary studies is not specified.