Planarian Behavioral Screening Data for Organophosphorus Pesticide Mixtures

21 binary mixtures of 7 organophosphorus pesticides were screened in adult and regenerating Dugesia japonica planarians. The dataset includes 22 readouts quantifying lethality, stickiness, and behavior on days 7 and 12 post-exposure, with comparisons to a Loewe concentration addition model. Authored by Danielle Ireland and last updated in March 2026, the data supports research into mixture toxicity and developmental neurotoxicity.

Use Cases

• Modeling mixture interactions (additive, synergistic, antagonistic) based on 22 behavioral and lethality readouts.
• Comparing toxicological susceptibility between adult and regenerating organisms based on developmental stage data.
• Correlating behavioral outcomes like stickiness with acetylcholinesterase inhibition measurements.
• Testing predictions of concentration addition models against experimental mixture toxicity data.

Strengths

• Includes 22 distinct quantitative readouts for each experimental condition.
• Tests 21 specific binary mixtures of 7 named organophosphorus pesticides.
• Compares results across two developmental stages (adult vs. regenerating planarians).
• Data is associated with a peer-reviewed scientific methodology described in the source PDF.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data format is PDF (1.3 MB), which may require extraction for computational analysis.

Provenance

Source

Danielle Ireland via figshare

Collection Method

Experimental screening using an automated platform on Dugesia japonica planarians exposed to pesticide mixtures.

Freshness

Last updated 2026-03-25 22:02:14